Boggs Center for Energy and BiotechnologyTulane University

Faculty: S. Michal Jazwinski, Ph.D.


Stanford University, Biochemistry, 1975

Professor of Medicine

Director, Center for Aging
Email: sjazwins@tulane.edu

Research Interests

Genetics of aging.

Recent Publications

A. Schulz, T. Mousallem, M. Venkataramani, D.A. Persaud-Sawin, A. Zucker, C. Luberto, A. Bielawska, J. Bielawski, J.C. Holthuis, S.M. Jazwinski, L. Kozhaya, G.S. Dbaibo, R.M. Boustany.  The CLN9 Protein, a Regulator of Dihydroceramide Synthase.  J. Biol. Chem. 281, 2784-2794 (2006).

H.C. Hsu, D.K. Scott, P. Zhang, J. Zhou, P. Yang, Q. Wu, H.W. Schroeder, Jr., L.B. Gerald, E. Ravussin, S.M. Jazwinski, J.D. Mountz, the Louisiana Healthy Aging Study.  CD8 T-Cell Immune Phenotype of Successful Aging.  Mech. Ageing Dev.  127, 231-239 (2006).

S. Spassieva, J.-G. Seo, J.C. Jiang, J. Bielawski, F. Alvarez-Vasquez, S.M. Jazwinski, Y.A. Hannun, L.M. Obeid.  Necessary Role for the Lag1p Motif in (Dihydro)Ceramide Synthase Activity.  J. Biol. Chem. 281, 33931-33938 (2006).

K.S. Hawley, K.E. Cherry, J. Su, Y.W. Chiu, S.M. Jazwinski for The Louisiana Healthy Aging Study.  Knowledge of Memory Aging in Adulthood.  Int. J. Aging Hum. Dev.  63, 317-334 (2006).

J.-G. Seo, C.-Y. Lai, M.V. Miceli, S.M. Jazwinski.  A Novel Role of Peroxin Pex6: Suppression of Aging Defects in Mitochondria.  Aging Cell 6, 405-413 (2007).

J.M. Fabre, R.H. Wood, K.E. Cherry, L.J. Su, M.E. Cress, C.M. King, M.J. deVeer, R.E. Gardner, S.M. Jazwinski for The Louisiana Healthy Aging Study.  Age-Related Deterioration in Flexibility Is Associated with Health-Related Quality of Life in Nonagenarians.  J. Geriatr. Phys. Therap.  30, 16-22 (2007).

C.E. Senkal, S. Ponnusamy, M.J. Rossi, J. Bielawski, D. Sinha, J.C. Jiang, S.M. Jazwinski, Y.A. Hannun, B. Ogretmen.  Role of Human Longevity Assurance Gene 1 and C-18 Ceramide in Chemotherapy-Induced Cell Death in Human Head and Neck Squamous Cell Carcinomas.  Mol. Cancer Ther. 6, 712-722 (2007).

M.I. Frisard, A. Broussard, S.S. Davies, L.J. Roberts, J. Rood, L. de Jonge, X. Fang, W.A. Deutsch, S.M. Jazwinski, E. Ravussin for The Louisiana Healthy Aging Study.  Aging, Resting Metabolic Rate and Oxidative Damage:  Results from the Louisiana Healthy Aging Study.  J. Geront. A Biol. Sci Med. Sci. 62, 752-759 (2007).

J. Dai, L. Li, S. Kim, B. Kimball, S.M. Jazwinski, J. Arnold for The Georgia Centenarian Study.  Exact Sample Size Needed to Detect Dependence in 2 x 2 x 2 Tables.  Biometrics 63, 1245-1252 (2007).

Y.Y. Liu, J.Y. Yu, D. Yin, G.A. Patwardhan, V. Gupta, Y. Hirabayashi, W. M. Holleran, S. M. Jazwinski, A. E. Giuliano, V. Gouaze-Andersson, D. P. Consoli, M.C. Cabot.  A Role of Ceramide in Driving Cancer Cell Resistance to Doxorubicin. FASEB J.  2008 Feb. 1 [epub ahead of print]

P. Tedesco, J. Jiang, J. Wang, S.M. Jazwinski, T.E. Johnson.  Genetic Analysis of hyl-1, the C. elegans homolog of LAG1/LASS1.  AGE  30, 43-52 (2008).

 

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